Big company, creator and master of much complexity, envelops small company, exhorter of keeping things simple.

I see 2 possible outcomes:

1. 37 Signals simply disappears forever.
2. 37 Signals simply disappears for a while, but encourages small pockets of simplicity throughout Microsoft. A few projects change slightly. Exchange meets Backpack, perhaps.

I have no idea how that would play out, but it certainly would be interesting.

EDIT: I should point out that I don’t really think MS should by 37S, I just think it’s an interesting acquisition to consider.  And so I added a “?” to the post title.